Biotechnology

Bi‐Phasic Switch‐Based Biosensor Chemistry

A novel chemistry which is both simple and adaptable to a broad range of biomarker detection applications.

Genome editing with the Type I CRISPR/Cas3 systems

Bi-directional genome editing with CRISPR Type I systems for gene knockouts, knock-ins, or knock ups. 

Gene editing with a multi-effector CRISPR Type I system

Use of Cascade holds promise for enhanced binding and reduced off target effects.

Thiosulfonate Switch Technique - a three step protocol for detection of S-nitrosylated proteins

Thiosulfonate switch technique: a new three step protocol for SNO detection in aqueous medium that traps protein S-nitrosothiols as mixed disulfides bearing a fluorescent probe at pH 4.0. 

Novel Dyes for Proteomic Research, Drug Development and Diagnostics

Researchers at Montana State University have developed optical labeling molecules - dyes - that possess increased detection sensitivity. These water-soluble Zwitterionic dyes also enable recovery of intact proteins and allow for versatile, high speed, multiplex analysis for proteomics.

Trimodal Handheld Probe Based on Raman Spectroscopy and Confocal Imaging for Cancer Detection

Jointly developed with Vanderbilt University.

A single handheld device for combined confocal imaging and confocal Raman spectroscopy as well as gross spatial imaging as a clinical diagnostic tool for cancer detection in humans, with a specific emphasis on the skin. 

Quaternary Ammonium Complex Provides Superior Broad Spectrum Antimicrobial Activity

Binding biocide to soluble dendrimers targets and disrupts the cell wall providing a new approach to controlling household, industrial, and medical microorganisms.

Mouse Monoclonal Antibodies

 Anti-gp91phox, Anti-p22phox and Anti- CAP-18

Optics/Photonics

Diode laser for low-cost identification of water in the lower atmosphere

Better weather forecasting with a micro-pulse differential absorption LIDAR (DIAL).

Discrimination of Herbicide-resistant Weeds with Hyperspectral Imaging

At Montana State University, an electrical engineering professor and a weed scientist have used funding from the state to develop a technology that can identify herbicide-resistant kochia, with the potential to save farmers $1 billion per year.  This technology is now available for licensing.

Trimodal Handheld Probe Based on Raman Spectroscopy and Confocal Imaging for Cancer Detection

Jointly developed with Vanderbilt University.

A single handheld device for combined confocal imaging and confocal Raman spectroscopy as well as gross spatial imaging as a clinical diagnostic tool for cancer detection in humans, with a specific emphasis on the skin. 

System for the Non-Destructive Removal of Radioactive Material from Challenging Porous Surfaces

Effectively and efficiently cleans natural and man-made porous material of radioactive contamination.

Flying Insect Detection and Identification

Laser-based detection system can monitor and discriminate flying insects.

Engineering

Large magnetic moment bcc FexCoyMnz ternary alloy thin films

Montana State University seeks a partner to license and commercialize a breakthrough metal alloy with magnetic moment up to 3.25 μB/atom—shattering the previous record of 2.45 μB/atom.

Low Cost Electrocardiogram (ECG/EKG) Training System

An affordable tool for training doctors, nurses, and first responders.

Radiation tolerant computer proven to work for Aerospace Applications

Montana State University has developed a small lightweight computer that can resist damage from radiation exposure from low-orbit to deep-space missions.

Increased Astaxanthin production in algal systems

MSU has developed a process to use bicarbonate to double the rate of astaxanthin production in commercial algal systems.

One-step bulk synthesis process for phosphorus (P)-doped graphitic carbon

 Low oxygen content and a widely-tunable phosphorus content may allow for use of this material as stable phosphorus-based electrodes or as a catalyst of the oxygen reduction reaction (ORR) in fuel cells.

Discrimination of Herbicide-resistant Weeds with Hyperspectral Imaging

At Montana State University, an electrical engineering professor and a weed scientist have used funding from the state to develop a technology that can identify herbicide-resistant kochia, with the potential to save farmers $1 billion per year.  This technology is now available for licensing.

Agriculture

MTF1435 Forage Winter Wheat

In 2018, Montana State University partnered with two seed companies to commercialize MTF1435, a winter wheat developed as a successor to the popular Willow Creek forage wheat variety.  Licensed territories include many western US states.  The variety is still available for International licensing.

FORAGE FX 1001 Nearly Awnless Winter Forage Triticale

Montana State University seeks an international partner to license and commercialize this forage variety outside the United States and Canada.

Small-seeded black fababean for cover crop use (14-24SB)

Montana State University seeks a commercial partner to PVP release, produce, and distribute the first small-seeded, dark-coated fababean for the cover crop market.

Discrimination of Herbicide-resistant Weeds with Hyperspectral Imaging

At Montana State University, an electrical engineering professor and a weed scientist have used funding from the state to develop a technology that can identify herbicide-resistant kochia, with the potential to save farmers $1 billion per year.  This technology is now available for licensing.

Controlling and Stabilizing Color, Shelf-life and Off-Flavoring in Wheat-Based Food Products

Montana State University is seeking wheat breeders interested in developing varieties where end-product food properties such as color, shelf-life and off-flavoring can be optimized. 

Research to Commercialization Collaboration Opportunity: Pre-Harvest Sprouting Resistant Wheat

Pre-harvest sprouting in wheat has a high economic cost for grain producers and end users. MSU researchers are seeking an industry collaborator to pursue two key genes regulating PHS.

Stem, Leaf, and Stripe Rust Resistance in Wheat

New germplasm has been developed based on a suite of homeologs to enhance bread wheat resistance to various rust pathogens.

Non‐Transgenic Mutations in Wheat to Create Grain Hardness Variations

A series of new puroindoline alleles via EMS mutagenesis that create defined levels of grain hardness and texture.   These alleles could be used to impart the following traits:

  • Group 1: Super soft wheat.  Decreased grain hardness of a soft wheat and increase in break flour yield, reduced starch damage and water absorption. 
  • Group 2: Enhanced milling yield soft wheat.  Increased grain hardness of a soft wheat to increase overall milling yield and reduce sifting time.
  • Group 3: High milling yield hard wheat.  Decreased grain hardness of a hard wheat increases overall milling yield and reduces flour ash levels.
  • Group 4: High water absorption hard wheat.  Increase grain hardness of a hard wheat increases starch damage in flour.