A primary goal of the TTO is to foster the development of Montana businesses based on MSU technology, inventions and research. To that end, more than 60 companies have been founded based in part on MSU intellectual property, with at least 50 direct spinout companies. Following is a sampling of some of those companies. The TTO looks forward to working with other companies or entrepreneurs interested in leveraging MSU assets.


NanoMagnetic Solutions develops advanced tools using force modulation to revolutionize pre-clinical drug discovery for brain diseases.
Resilient Computing logo
Resilient Computing was founded in 2020 in order to commercialize computing technology that has been developed under the direction of Professor Brock LaMeres.  Dr. LaMeres' MSU research team has spent over a decade investigating techniques to increase the resilience of computers in adverse conditions.  Applications of this research include high-performance space computing and malware-resistant embedded computers.  
turtle island tales logo
Turtle Island Tales provides health and wellness educational material for American Indian families with young children. Our ingredients for a healthy family include inspiring stories, recipes, games, and parenting help.
BLOCKY’s data lineage tooling lets you build trust in your data. You can use our APIs to easily introduce blockchain-based immutability to your storage systems and business processes. As a result, you can prove the integrity of your data and build trust with your customers and partners. Pallets is our first product which provides data integrity certificates, acting as a programmable notary for digital data.
Success Prints makes games that give students the tools to draft their unique blueprint for success in higher education.  MSU Professor Tricia Seifert created a powerful boardgame to teach high school and college students the tools they need to succeed in college.  Feedback from participants and educators was very positive, which left a challenge--how to make and distribute the game.  Together with a team of entrepreneurial MSU graduates at Magic Sail Games, Success Prints is meeting this challenge, and more.
Revibro logo
Revibro aims to manufacture the fastest tunable optic in the world.
Agile Focus Designs logo
Agile Focus Designs automates and accelerates microscopic imaging with fast focus and zoom technology without any moving parts. This electronic control of true optical zoom and focus without complex algorithms revolutionizes the way microscopes can be used.

Psquare Scientific

Psquare Scientific develops next-generation tools for measuring bioactivity of herbal products.  There are a significant number of immune responses that can be generated by our bodies when we consume herbal supplements.  Psquare Scientific was founded with the goal of supporting consumer's decisions when purchasing these supplements.  By providing state-of-the-art testing services, we can all make educated decisions about what supplements to feed to both ourselves and our families.
nature's fynd logo
Nature's Fynd is a company that develops microbe-based proteins for meat substitutes and dairy substitutes. The protein is produced by a fungus first identified in geothermal springs in Yellowstone National Park.
NWB Sensors logo

NWB Sensors is focused on building high accuracy environmental sensors, designed specifically to improve decision-making related to resource management.

NWB currently offers cloud imaging systems, high quality environmental monitoring stations, and data analysis as a service. NWB is developing liquid-less snowpack sensors, image-based mapping systems, and integrated machine learning technology for land resource management.

Bridger Photonics
Bridger Photonics was founded by three dedicated laser physicists who pursued their advanced degrees together at Montana State University. Each of the founders subsequently pursued different paths, developing unique sets of experience along the way, and reunited to build a company with a strong set of core values reflecting the pioneering spirit of Bozeman, Montana. The company has several licenses with MSU and is researching and developing a variety of technologies based around its proprietary monolithic lasers and its novel actively stabilized frequency swept lasers. With unsurpassed capabilities in terms of precisions, Bridger is becoming a world leader in LIDAR for remote gas sensing, LADAR for precision distance measurements, and methods for advanced imaging including focus control and 3D imaging.
S2 Corporation
S2 provides creative ultra-wideband sensing and signal processing solutions for multiple customers. The company has a depth of experience in research and development, simulation, proof of concept designs, rapid prototyping and external testing. Applications for S2 technologies include radar range-Doppler signal processing, surveillance and signal intelligence for electronic warfare, and related applications, signal processing for broadband pulsed laser radar, optical communications, and multi-static continuous wave laser radar. Emerging technology applications include analog-to-digital conversion, arbitrary waveform generation, and true-time delay for RF beamforming. Supporting technology development efforts include cryogenics engineering and RF and digital components, among others.
Montana Microbial Products
Montana Microbial Products is commercializing technology for use in sustainable agricultural and aquaculture systems. The company works with microbial agents and compounds discovered and developed by MMP, licensed from universities or others, and also does contract research and development. MMP operates a fully functional microbiology lab and pilot plant. Core technical competencies include isolation and selection technology, formulation, solid and liquid fermentation, and process design. The two principals in the company, Cliff Bradley and Bob Kearns, have experience taking products from discovery, through production to commercialization, including international sales and licensing.
Cleanwaste, a 10-year old manufacturer in Belgrade, Montana makes products that help people cope with human waste "when plumbing's not available®". Starting with four founders, Cleanwaste today employs 56 full-time employees, having grown from 18 in the last several months. Cleanwaste supplies US military, outdoor retail chains, emergency and disaster-relief entities, industrial, mining and utilities markets, institutional healthcare buyers and even mass market drug retail chains. Cleanwaste currently is the largest supplier of human waste handling products to the US military, outdoor and healthcare markets.
Ligocyte Pharmaceuticals, Inc

Ligocyte Pharmaceuticals, Inc. (a start-up from MSU, acquired by Takeda Pharmaceutical Company Limited)

Despite the significant progress made in the vaccine industry to date, two challenges remain: to produce vaccines against unmet or emerging targets, and to produce improved vaccines that are more effective than currently available products. LigoCyte has developed proprietary technologies that address both of these challenges. LigoCyte focuses on virus-like particle (VLP) vaccines that mimic viruses but lack the ability to reproduce or cause infectious complications. VLP-based vaccines have had a tremendous impact on both human health and the industry itself, as evidenced by medical and commercial success in the human papillomavirus and Hepatitis B fields. LigoCyte's core technologies are contributing to the development of vaccine products against norovirus, influenza, and other respiratory viruses.
BioSurface Technologies Corporation
BioSurface Technologies Corporation provides innovative products that grow, measure, and evaluate biofilms and biofilm processes to aid product development and process control, and to increase our understanding of fundamental biofilm processes. BioSurface Technologies is providing products and technology to industry and researchers world-wide, including its CDC Biofilm Reactor® and Drip Flow Biofilm Reactor®.
406 Aerospace Logo

406 Aerospace (acquired by Tyvak)

406 Aerospace was a science and engineering company focused on applying state-of-the art technologies to enable more capable autonomous flight systems.  The company, founded in 2011 by a Montana State Research Professor of Physics and a Systems Engineer, had its roots in Montana State University's Space Science and Engineering Laboratory. The company specified, designed, built, and qualified for end-use both hardware and software for application to autonomous robotic systems, with primary focus on small, yet highly capable, low-mass and low-power spacecraft and unmanned aerial systems for commercial and government clients.